Ukwenziwa kanye nokulawulwa kwamaprotheni kuncike ezidingweni zokusebenza kwamaseli. Umklamo wamaprotheni ugcinwa ku-DNA, esetshenziswa njengesifanekiso sokukhiqizwa kwe-RNA yesithunywa ngenqubo elawulwa kakhulu yokubhala. Ukubonakaliswa kwamaprotheni kuyinqubo lapho amaprotheni aguqulwa khona, ahlanganiswe futhi alawulwa.Amaprotheniinkulumo ibhekwa njengengxenye ebalulekile ye-proteomics, eyenza amaprotheni ahlanganiswe kabusha aboniswe ezinhlelweni zokusingatha ezahlukene. Ngaphezu kwalokho, kunezindlela ezintathu zokukhuluma kabusha kwamaprotheni, njenge-chemical protein synthesis, in vivo protein expression kanye ne-in vitro protein expression. Izikhungo zocwaningo ezisekelwe ku-Biotechnology ikakhulukazi zithembele ekuvezeni amaprotheni ukuze zakhe izindlela zokwelapha ezintsha ezinemiphumela engemihle emincane.

Umbiko wemakethe ye-protein expression we-global wehliswa ngamasistimu wokusingathwa kwamaprotheni, izinhlelo zokusebenza, abasebenzisi bokugcina, nezifunda namazwe. Ngokusekelwe ohlelweni lokusingathwa kwamaprotheni, imakethe ye-protein expression global ingahlukaniswa ngeyeast expression, i-mammalian expression, i-algae expression, i-insect expression, i-bacterial expression kanye ne-cell-free expression. Ngokusho kwesicelo, imakethe ihlukaniswe isiko lamaseli, ukuhlanzwa kwamaprotheni, amaprotheni e-membrane kanye nobuchwepheshe bokudlulisela. Ngokusho kwabasebenzisi bokugcina, i-protein expression global ingahlukaniswa ngezinhlangano zocwaningo lwenkontileka yokutholwa kwezidakamizwa, izikhungo zemfundo kanye nezinkampani zemithi.

Izifunda ezimbozwe yilo mbiko wemakethe ye-protein expression yiNyakatho Melika, i-Europe, i-Asia Pacific nezinye izifunda zomhlaba. Ngokwezinga lamazwe/izifunda, imakethe yokusho amaprotheni ingahlukaniswa ibe yi-United States, Mexico, Canada, United Kingdom, France, Germany, Italy, China, Japan, India, Southeast Asia, Gulf Cooperation Council, Africa. , njll.

Ukusabalala kwezifo ezingamahlalakhona kungenye yezinto eziphambili eziqhuba ukukhula kwemakethe yokusho amaprotheni emhlabeni jikelele.

Ukukhula okusheshayo kwezinguquko endleleni yokuphila kanye nezici zemvelo yizona zinto ezihamba phambili eziqhuba ukukhula kwemakethe yokusho amaprotheni. Ukwenyuka kwemisebenzi yocwaningo emkhakheni wezokwelapha, kanye nokukhula kwesibalo sabantu asebekhulile kanye nokusabalala kwezifo ezingamahlalakhona ngezinye zezinto ezibalulekile ezengeza ukukhula kwemakethe. Izinguquko zomzimba ezenzeka ngokukhula zenza asebekhulile amathuba okuba babe nezifo ezingelapheki njengomdlavuza. Ngakho-ke, izigameko zomdlavuza emhlabeni wonke kulindeleke ukuthi zikhule ngokuguga kwesibalo sabantu. Kodwa-ke, izindleko eziphezulu zocwaningo lwe-proteomics zingathiya ukukhula kwemakethe ye-protein expression expression. Noma kunjalo, ukuthuthuka okuqhubekayo kwezobuchwepheshe emkhakheni wesayensi yezempilo kungadala amathuba amaningi okuthuthuka kwemakethe.

Ngenxa yokukhula kwezimali ocwaningweni lwesayensi yezempilo kulesi sifunda, iNyakatho Melika kulindeleke ukuthi ibuse imakethe yokusho amaprotheni emhlabeni jikelele. Izimali eziqoqwe yizinhlangano ezizimele nezikahulumeni zocwaningo lwebhayoloji kulindeleke ukuthi zikhuthaze ukukhula kwale makethe. I-Europe ilandela iNyakatho Melika, kanti ukwanda kwesifo sikashukela kulesi sifunda kulindeleke ukuthi kuqhubekisele phambili ukukhula kwemakethe. Ngokwesibonelo; Ngokwe-World Health Organization; eYurophu, bekunamacala amasha omdlavuza we-4,229,662 ngo-2018. Ngaphezu kwalokho, ngenxa yokwanda kwezifo ezingapheli kanye nokwanda kwabantu asebekhulile esifundeni, isifunda sase-Asia-Pacific kulindeleke ukuthi sibonise ukukhula okuphezulu kakhulu ekukhulumeni kwamaprotheni emhlabeni wonke. imakethe.

Izinzuzo eziyinhloko zombiko wemakethe ye-protein global-•Umbiko wemakethe ye-protein expression uhlanganisa ukuhlaziywa okujulile komlando nokubikezela. • Umbiko womhlaba wonke wocwaningo lwemakethe ye-protein expression unikeza ulwazi oluningiliziwe mayelana nesingeniso semakethe, isifinyezo semakethe, imali engenayo yemakethe yomhlaba wonke (reven ue USD), abashayeli bemakethe, izingqinamba zemakethe, amathuba emakethe, ukuhlaziya ukuncintisana, izinga lesifunda nezwe. • Umbiko wemakethe yomhlaba wonke we-protein expression usiza ukuhlonza amathuba emakethe. • Umbiko wemakethe yomhlaba wonke we-protein expression uhlanganisa ukuhlaziya okubanzi kwamathrendi asafufusa kanye nesimo sokuncintisana.

Ngesistimu yokusingatha i-protein expression:•Yeast expression•Mammalian expression•algae expression•insect expression•bacteria expression•cell-free expression

Ngokusebenzisa: • Isiko lamaseli •Ukuhlanzwa kwamaprotheni• Amaprotheni e-Membrane • Ubuchwepheshe bokudlulisa

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