Nucleic acid extractor chiridzwa chinoshandisa kuenzanisa nucleic acid yekubvisa reagents kuti ipedze otomatiki sampuli nucleic acid kutorwa. Inoshandiswa zvakanyanya munzvimbo dzakasiyana siyana dzakadai seCentre for Disease Control, kuongororwa kwechirwere chekiriniki, kuchengetedzeka kwekuwedzerwa ropa, chiziviso chezvemitemo, kuongorora hutachiona hwemamiriro ekunze, kuongororwa kwekuchengetedza chikafu, kupfuya mhuka uye kutsvagisa mamorekuru biology.

1. Yakakamurwa zvichienderana nehukuru hwechiridzwa chechiridzwa

1)Automatic liquid workstation

Iyo otomatiki yemvura yekushandira chishandiso chine simba kwazvo, icho chinongopedzisa kugovera uye kushuvira kwemvura, uye inogona kutoona yakazara otomatiki yemuenzaniso kudhirowa, kukwidziridza, uye kuona nekubatanidza mabasa akadai sekusimudzira uye kuona. Nucleic acid extraction ingori imwe chete yekushanda kwayo, uye haina kukodzera kudhirowa murabhoritari ye nucleic acid. Inowanzo shandiswa kune zvinodiwa zvekuedza zvemhando imwe chete yemuenzaniso uye yakawanda kwazvo yezvienzaniso (inenge 96, kazhinji mazana akati wandei) panguva. Iyo yekumisikidzwa kwepuratifomu uye kushanda kweotomatiki workstations inoda mari yakakura.

2)Diki otomatiki nucleic acid extractor

Iyo diki-chiyero chigadziriso chiridzwa chinozadzisa chinangwa chekuburitsa otomatiki nucleic acid kuburikidza nehunyanzvi hwechimiro chekushanda, uye inogona kushandiswa mune chero marabhoritari.

2. Siyana maererano nemusimboti wekubvisa

1)Zviridzwa zvinoshandisa spin column nzira

Iyo centrifugal column nzira nucleic acidextractor inonyanya kushandisa musanganiswa wecentrifuge uye otomatiki pipetting mudziyo. The throughput kazhinji 1-12 samples. Nguva yekushanda yakafanana neyekutora nemaoko. Hainatsiridzi kushanda kwechokwadi uye inodhura. Mienzaniso yakasiyana-siyana Zvishandiso zvechiridzwa hazvisi pasi rose, uye zvinongokodzera ma laboratori makuru ane mari yakakwana.

2) Zviridzwa zvinoshandisa magineti bead nzira

Kushandisa magineti beads semutakuri, uchishandisa musimboti wemagineti beads adsorbing nucleic acids pasi pemunyu wakanyanya uye yakaderera pH kukosha, uye kuaparadzanisa kubva nucleic acids pasi pemunyu wakaderera uye yakakwirira pH kukosha, iyo yose nucleic acid kutorwa uye kucheneswa maitiro kunoitika nekufamba. magineti bead kana kutamisa mvura. Nekuda kwekusiyana kweiyo musimboti wayo, inogona kugadzirwa mumhando dzakasiyana-siyana, iyo inogona kutorwa kubva kune imwechete chubhu kana kubva ku8-96 samples, uye kushanda kwayo kuri nyore uye nekukurumidza. Zvinongotora 30-45 maminetsi kuti abudise 96 samples, iyo inovandudza zvikuru Kubudirira kwekuedza uye mutengo wakaderera unobvumira kuti ishandiswe mumarabhoritari akasiyana. Parizvino ndicho chiridzwa chikuru pamusika.