Oligonucleotide (Oligonucleotide), muri rusange yerekeza ku gice cya polinucleotide igizwe n'ibice 2-10 bya nucleotide bisigara bifitanye isano na fosifori, ariko iyo iri jambo rikoreshejwe, umubare w’ibisigisigi bya nucleotide Nta mategeko akomeye. Mubitabo byinshi, molekile ya polinucleotide irimo ibisigazwa bya nucleotide 30 cyangwa birenga nabyo bita oligonucleotide. Oligonucleotide irashobora guhita ikomatanya nibikoresho. Birashobora gukoreshwa nka ADN synthesis synthesis, gene gene, nibindi, kandi bifite uburyo bwinshi bwo gukoresha mubushakashatsi bwibinyabuzima bigezweho.

Porogaramu

Oligonucleotide ikoreshwa nka probe kugirango imenye imiterere ya ADN cyangwa RNA, kandi ikoreshwa mubikorwa nka chip chip, electrophoreis, na fluorescence muburyo bwo kuvanga.

ADN ikomatanyirizwa na oligonucleotide irashobora gukoreshwa mumurongo wa polymerisiyonike, ishobora kwongerera no kwemeza ibice hafi ya byose bya ADN. Muri ubu buryo, oligonucleotide ikoreshwa nka primer kugirango ihuze nibice byuzuzanya byanditse muri ADN kugirango ikore kopi ya ADN. .

Oligonucleotide igenga ikoreshwa mu guhagarika ibice bya RNA no kubirinda guhindurwa muri poroteyine, bishobora kugira uruhare runini mu guhagarika ibikorwa by'uturemangingo twa kanseri.