Kwipimisha aside nucleique mubyukuri nukumenya niba hari aside nucleic (RNA) ya coronavirus nshya mumubiri wikizamini. Acide nucleic ya buri virusi irimo ribonucleotide, kandi umubare na gahunda ya ribonucleotide ikubiye muri virusi zitandukanye biratandukanye, bigatuma buri virusi yihariye.
Acide nucleic ya coronavirus nshya nayo irihariye, kandi kumenya aside nucleic ni byo byerekana neza aside nucleique ya coronavirus nshya. Mbere yo gupima aside nucleic, ni ngombwa gukusanya ingero z'umusemburo w'isomo, umuhogo wo mu muhogo, amazi ya bronchoalveolar lavage, amaraso, n'ibindi, kandi mugupima izo ngero, ushobora gusanga inzira z'ubuhumekero zanduye zanduye bagiteri. Kumenya neza coronavirus nucleic acide ikoreshwa muburyo bwo kumenya umuhogo swab sample. Icyitegererezo cyacitsemo ibice kandi gisukuwe, kandi hashobora kuvamo aside nshya ya coronavirus nucleic aside, kandi imyiteguro yikizamini iriteguye.

Kumenya acide ya coronavirus nucleic ikoresha cyane cyane tekinoroji ya RT-PCR ya fluorescence, ikaba ari ihuriro rya tekinoroji ya PCR ya PCR na tekinoroji ya RT-PCR. Mubikorwa byo gutahura, tekinoroji ya RT-PCR ikoreshwa muguhindura kwandukura aside nucleic (RNA) ya coronavirus nshya muri acide deoxyribonucleic ihuye (ADN); noneho tekinoroji ya fluorescence PCR ikoreshwa mukwigana ADN yabonetse kubwinshi. ADN yakuweho iramenyekana kandi yanditseho iperereza ryimibonano mpuzabitsina. Niba hari aside nshyashya ya coronavirus nucleic, igikoresho gishobora kumenya ibimenyetso bya fluorescent, kandi, nkuko ADN ikomeza kwigana, ibimenyetso bya fluorescent bikomeje kwiyongera, bityo bikamenyekana muburyo butaziguye ko coronavirus nshya ihari.