Kaphatikizidwe ndi kuwongolera kwa mapuloteni kumadalira magwiridwe antchito a maselo. Mapangidwe a mapuloteni amasungidwa mu DNA, yomwe imagwiritsidwa ntchito ngati template yopangira messenger RNA ndi ndondomeko yolembedwa bwino kwambiri. Kufotokozera kwa mapuloteni ndi njira yomwe mapuloteni amasinthidwa, kupangidwa ndi kuyendetsedwa.Mapulotenimawu amaonedwa kuti ndi gawo lofunika kwambiri la proteinomics, lomwe limathandizira kuti mapuloteni ophatikizananso awonetsedwe m'machitidwe osiyanasiyana. Kuphatikiza apo, pali njira zitatu zowonetseranso mapuloteni, monga kaphatikizidwe ka protein protein, mu vivo protein expression ndi in vitro protein expression. Mabungwe ofufuza a Biotechnology makamaka amadalira kufotokoza kwa mapuloteni kuti apange mankhwala atsopano omwe alibe zotsatirapo zochepa.
Lipoti la msika wapadziko lonse wa protein expression waphwanyidwa ndi ma protein expression host system, ntchito, ogwiritsa ntchito mapeto, ndi zigawo ndi mayiko. Kutengera dongosolo lama protein expression host, msika wapadziko lonse lapansi wama protein expression ukhoza kugawidwa m'mawu a yisiti, mawu a mammalian, mawu a algae, mawonekedwe a tizilombo, mawonekedwe a bakiteriya komanso mawu opanda ma cell. Malinga ndi kugwiritsa ntchito, msika wagawika m'maselo am'maselo, kuyeretsa mapuloteni, mapuloteni a membrane ndi ukadaulo wa transfection. Malinga ndi ogwiritsa ntchito omaliza, mafotokozedwe a mapuloteni apadziko lonse lapansi atha kugawidwa m'mabungwe ofufuza zachipatala, mabungwe amaphunziro ndi makampani opanga mankhwala.
Madera omwe akhudzidwa ndi lipoti la msika wama protein awa ndi North America, Europe, Asia Pacific ndi madera ena padziko lapansi. Malinga ndi kuchuluka kwa mayiko / madera, msika wamapuloteni ukhoza kugawidwa ku United States, Mexico, Canada, United Kingdom, France, Germany, Italy, China, Japan, India, Southeast Asia, Gulf Cooperation Council, Africa. , ndi zina.
Kuchuluka kwa matenda osachiritsika ndi chimodzi mwazinthu zazikulu zomwe zikuyendetsa kukula kwa msika wapadziko lonse lapansi wama protein.
Kukula mwachangu kwakusintha kwa moyo komanso zinthu zachilengedwe ndizomwe zimayambitsa kukula kwa msika wama protein. Kuchulukitsa kwa kafukufuku pazamankhwala, komanso kukula kwa okalamba komanso kuchuluka kwa matenda osachiritsika ndi zina mwazinthu zomwe zimathandizira kukula kwa msika. Kusintha kwa thupi komwe kumachitika ndi ukalamba kumapangitsa okalamba kukhala ndi mwayi wokhala ndi matenda osatha monga khansa. Chifukwa chake, chiwopsezo cha khansa padziko lonse lapansi chikuyembekezeka kukwera ndi ukalamba wa anthu. Komabe, kukwera mtengo kwa kafukufuku wa proteinomics kumatha kulepheretsa kukula kwa msika wapadziko lonse lapansi wama protein. Komabe, kupita patsogolo kwaukadaulo mu gawo la sayansi ya moyo kumatha kubweretsa mwayi wambiri wopititsa patsogolo msika.
Chifukwa chakuchulukirachulukira kwa ndalama pakufufuza kwa sayansi ya moyo mderali, North America ikuyembekezeka kulamulira msika wapadziko lonse lapansi wama protein. Ndalama zoperekedwa ndi mabungwe azinsinsi komanso aboma zofufuza zachilengedwe zikuyembekezekanso kulimbikitsa kukula kwa msika uno. Europe ikutsatira North America, ndipo kuchuluka kwa shuga m'derali kukuyembekezeka kulimbikitsa kukula kwa msika. Mwachitsanzo; Malinga ndi World Health Organisation; ku Ulaya, panali milandu yatsopano ya khansa ya 4,229,662 mu 2018. Kuwonjezera apo, chifukwa cha kuwonjezeka kwa matenda aakulu komanso kuwonjezeka kwa anthu okalamba m'derali, dera la Asia-Pacific likuyembekezeka kusonyeza kukula kwakukulu kwa mapuloteni apadziko lonse. msika.
Ubwino waukulu wa lipoti la msika wapadziko lonse wa protein expression-•Lipoti la msika wapadziko lonse wa protein expression limafotokoza mozama mbiri yakale komanso kusanthula kwamtsogolo. • Lipoti la kafukufuku wamsika wapadziko lonse wa protein expression limapereka chidziwitso chatsatanetsatane chokhudza kuyambika kwa msika, chidule cha msika, ndalama zamsika zapadziko lonse lapansi (reven ue USD), oyendetsa msika, zovuta zamsika, mwayi wamsika, kusanthula kwapikisano, madera ndi dziko. • Lipoti la msika wapadziko lonse wa protein expression limathandizira kuzindikira mwayi wamsika. • Lipoti la msika wapadziko lonse wa protein expression limafotokoza zambiri za zomwe zikuchitika komanso momwe akupikisana.
Kupyolera mu dongosolo la protein expression host:•Yeast expression•Mammalian expression•algae expression•insect expression•mabacteria expression•cell expression
Pogwiritsa ntchito: • Chikhalidwe cha ma cell •Kuyeretsa mapuloteni• Puloteni ya Membrane • Ukadaulo wa Transfection
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Nthawi yotumiza: Dec-11-2020