Ko te B&M SAX he pou tangohanga whakawhiti anion kaha me te hiera silica, kei a ia te roopu mahi tote ammonium quaternary. Ka whakamahia te nuinga mo te tangohanga o nga pūhui anionic ngoikore, penei i te waikawa carboxylic. Ka taea te whakamahi i te whakawhiti anion kaha ki te tango i te utu kino mai i te wai me te wairewa kore-wai, ina koa mo te tangohanga o te waikawa ngoikore. He maha nga wa ka whakamahia ki te tango i nga anion kaha (waikawa pararopi, nucleotides, waikawa nucleic, pakiaka waikawa sulfonic, tote parakore, me etahi atu) i roto i te tauira, me te whakakorenga macromolecule koiora.