ʻO ka hoʻāʻo ʻana i ka waikawa nucleic e ʻike inā aia ka nucleic acid (RNA) o ka coronavirus hou i loko o ke kino o ke kumuhana hoʻāʻo. Aia nā ribonucleotides i loko o ka waikawa nucleic o kēlā me kēia maʻi, a ʻokoʻa ka helu a me ka hoʻonohonoho ʻana o nā ribonucleotides i loko o nā maʻi like ʻole, e hoʻohālikelike ʻia kēlā me kēia maʻi.
He kū hoʻokahi nō ka waikawa nucleic o ka coronavirus hou, a ʻo ka ʻike nucleic acid ka ʻike kikoʻī o ka nucleic acid o ka coronavirus hou. Ma mua o ka hoʻāʻo ʻana i ka waika nucleic, pono e hōʻiliʻili i nā laʻana o ka sputum o ke kumuhana, ka ʻāʻī ʻāʻī, ka wai holoi holoi bronchoalveolar, ke koko, a me nā mea ʻē aʻe, a ma ka hoʻāʻo ʻana i kēia mau laʻana, hiki ke ʻike ʻia ua loaʻa ka maʻi hanu o ke kumuhana i ka bacteria. Hoʻohana maʻamau ka ʻike ʻana i ka waikawa nucleic coronavirus hou no ka ʻike ʻana i ka laʻana o ka puʻu. Hoʻokaʻawale ʻia ka laʻana a hoʻomaʻemaʻe ʻia, a lawe ʻia ka waika nucleic coronavirus hou mai ia mea, a ua mākaukau nā mākaukau no ka hoʻāʻo.

Hoʻohana nui ka ʻike ʻana o ka nucleic acid hou i ka ʻenehana RT-PCR fluorescence quantitative, ʻo ia ka hui pū ʻana o ka ʻenehana PCR fluorescence quantitative a me ka ʻenehana RT-PCR. Ma ke kaʻina hana ʻike, hoʻohana ʻia ka ʻenehana RT-PCR e hoʻohuli i ka palapala nucleic acid (RNA) o ka coronavirus hou i loko o ka deoxyribonucleic acid (DNA); a laila hoʻohana ʻia ka ʻenehana PCR fluorescence quantitative e hana hou i ka DNA i loaʻa i nā mea nui. ʻIke ʻia ka DNA i hoʻopili ʻia a hoʻopaʻa inoa ʻia me kahi hoʻopaʻa wahine. Inā loaʻa kahi waikawa nucleic coronavirus hou, hiki i ka mea kani ke ʻike i ka hōʻailona fluorescent, a, i ka hoʻomau ʻana o ka DNA, hoʻomau ka piʻi ʻana o ka hōʻailona fluorescent, no laila ke ʻike ʻole nei i ka hele ʻana o ka coronavirus hou.